Cheap Flights from St. Louis to San Francisco
Flights from St. Louis to San Francisco
Sorted by price. All fares round-trip unless noted.
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Search St. Louis → San FranciscoCould two one-way tickets be cheaper?
On many routes, buying separate outbound + return one-ways beats the round-trip. Different airlines price each direction independently, so the split is sometimes $50–$200 cheaper.
Run the split-fare checkFrequently asked questions
How much does it cost to fly from St. Louis to San Francisco?+
Prices from St. Louis to San Francisco vary by season, airline, and how far ahead you book. Searching 4–6 weeks out typically yields the lowest fares.
Are there nonstop flights from St. Louis to San Francisco?+
Nonstop availability on this route varies by season. Many connections route through major hubs. Use filters in the full search to check nonstop-only options.
What is the cheapest day to fly from St. Louis to San Francisco?+
Tuesdays and Wednesdays are typically the cheapest departure days across most routes. Saturdays tend to be the most expensive. Even shifting your departure by 1–2 days can save $40–$80.
What is split-fare and can it save money on St. Louis to San Francisco?+
Split-fare means booking two separate one-way tickets instead of one round-trip. Different airlines price outbound and return legs independently, so the combination can be cheaper. Hopfare's split-fare engine checks this automatically — on many routes it saves $50–$200.
Which airlines fly from St. Louis to San Francisco?+
Multiple airlines serve this route. Use the full search above to see today's available carriers and compare prices.
Search St. Louis → San Francisco
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